Early Multi-Target Treatment of Mild-to-Moderate COVID-19, Particularly in Terms of Non-Steroidal Anti-Inflammatory Drugs and Indomethacin
نویسندگان
چکیده
Recently, in Italy, a flowchart to be used by General Practitioners for the at-home treatment of patients with COVID-19, has been released. It states that early SARS-CoV-2 infection is possible due availability specific antiviral drugs at-risk patients, and non-steroidal anti-inflammatory (NSAIDs) have an important function combating virus. Therefore, use NSAIDs not only rational but also effective cases cannot treated using antivirals. These seemingly simple concepts applied Italy since beginning pandemic doctors belong Italian groups created order help COVID-19 at home, time organizational difficulties within health institutions government. However, this approach was largely boycotted both Ministry Health medical institutions, which mainly suggested paracetamol as symptomatic, wait-and-watch first three days from onset symptoms. In article, we analyze rationale and, particular, multi-targeted including indomethacin synergism flavonoids low-dose aspirin, COVID-19. Applying these could reduced high lethality disease during two years prevented hospital overload. perspective, it still necessary systematically address comparison between different therapeutic approaches viral on experimental basis.
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ژورنال
عنوان ژورنال: BioMed
سال: 2023
ISSN: ['2673-8430']
DOI: https://doi.org/10.3390/biomed3010015